Los Angeles Angels at Washington Nationals MLB Prediction, Picks & Odds for Sept. 11, 2026

The Washington Nationals have been away from home for six games now, but on Friday they’ll finally make their return to open a three-game series against the Los Angeles Angels at 6:45 p.m. ET at Nationals Park. Washington has now lost seven straight, leaving the Nationals hunting for their first win since Sept. 1.

The home team had won the previous four meetings between the Nationals and San Diego Padres, and the Padres kept that trend alive on Wednesday. Washington suffered a 9-2 defeat.

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CJ Abrams certainly played a role in the loss, going 0-for-4 with three strikeouts. He hasn’t been driving in runs at the same clip lately: He’s totaled four RBIs in his last 22 games compared to 91 in his previous 117.

Meanwhile, the Angels beat the Boston Red Sox with six runs on Tuesday and decided to stick to that total again on Wednesday, edging Boston 6-4.

The Angels enjoyed a great performance from Ryan Johnson, who pitched six innings while giving up three earned runs on five hits.

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At the plate, the Angels let Denzer Guzman and Zach Neto run wild. Guzman went 3-for-4 with a home run and two runs, while Neto finished 2-for-3 with a home run and three RBIs. Neto has been coming through with runners on lately, racking up 19 RBIs in his last 20 games compared to 53 in his previous 121.

Los Angeles is now 56-90, having gone 3-2 since its three-game losing streak ended. Washington, meanwhile, has lost 15 of its last 16 road games, dropping to 67-81 this season.

Washington beat Los Angeles 7-4 in their last meeting on June 29, 2025. Will the Nationals repeat their success, or do the Angels have a better game plan this time around?

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How to Watch Los Angeles Angels at Washington Nationals

• TV: Angels.TV (road), Nationals.TV (home)

• Streaming: Stream on Fubo

• Buy tickets: Buy Angels at Nationals tickets on Gametime

Probable Starting Pitcher Analysis

Cade Cavalli (WSH)

2026 Season Stats: 12-5 | 3.12 ERA | 1.18 WHIP | 10.5 K/9

• No decision in last start on Sept. 5 @ LAD: 6 IP, 2 ER, 4 H

• 4-0, 1.75 ERA in last six starts; 8-5, 3.52 ERA in prior 24 games

• High run support: 6.4 per game this season

Yusei Kikuchi (LAA)

2026 Season Stats: 1-5 | 4.96 ERA | 1.47 WHIP | 9.0 K/9

• Won last start on Sept. 5 @ PIT: 6 IP, 0 ER, 5 H

• 4.96 earned run average this season; 3.99 last season

• Pitching with 5 days rest

• Last start vs. WSH (with TOR) (May 3, 2024, road): (ND) 6 IP, 1 ER, 6 H

Los Angeles Angels vs. Washington Nationals Betting Odds

• Moneyline: LAA +127 / WSH -156

Betting lines as of 09/11/2026 at 4:25 AM ET. Odds subject to change. Bet with bet365.

Los Angeles Angels Stat Check: Who’s Hot, Who’s Not

Who’s Hot

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Who’s Not

• Vaughn Grissom Previous Game: 0-4

  • .182/.280/.227 in last six games; .249/.310/.395 in prior 96 games

• Jose Siri: .119/.178/.190 since Aug. 22; .255/.310/.455 in prior 62 games

Washington Nationals Stat Check: Who’s Hot, Who’s Not

Who’s Hot

• Dylan Crews: 5-11, 2 2B in last three games; .217/.288/.361 in prior 90 games

Who’s Not

• Daylen Lile Previous Game: 0-4

  • 0-11 in last three games; .254/.307/.440 in prior 143 games

• Nasim Nuñez: .101/.168/.110 since July 28; .250/.333/.293 in prior 93 games

Last 10 Games for Los Angeles Angels (4-6)

Last 10 Games for Washington Nationals (2-8)

Final Score Prediction for Los Angeles Angels @ Washington Nationals on Sept. 11, 2026

Angels 3 – Nationals 5

Lean: Nationals

Give us the Nationals, as we like Cade Cavalli to build on that strong last start.

Disclosure: Some or all of this content may have been generated by AI. While we strive for accuracy, AI can occasionally produce incorrect information. If you buy something via one of our links, we may earn a commission.

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This story was originally published by Athlon Sports on Sep 11, 2026, where it first appeared in the MLB section. Add Athlon Sports as a Preferred Source by clicking here.